If researchers continued feeding the mice cuprizone for 12 weeks, degrees of the inflammatory aspect and its receptor dropped significantly. At 12 weeks the mice were also struggling to restore myelin, suggesting a potential connection between myelin fix and CXCR4. Related StoriesResearchers successfully restoration nerve cell damage in Alzheimer's dementiaStudy reveals mechanism behind protein-related diseasesGriffith University uncovers initial 3-D picture of protein associated with cancer spread’This was a surprise, as the main issue CXCR4 has been known for is its role in forming the mind, not healing the mind,’ Klein says. ‘But we did know that injury escalates the number of human brain cells that make CXCR4, so that it wasn’t an unreasonable place to look.’ Klein demonstrated that the cells destined to be repair and oligodendrocytes myelin harm, known as neural precursor cells, possess high levels of the CXCR4.In the case of acute aspirin poisoning, symptom severity can be predicted by the dosage ingested. Less than 150 milligrams of aspirin per kilogram of body weight – no symptoms to mild toxicity Ingestions of 150-300 mg/kg – slight to moderate toxicity Ingestions of 300-500 mg/kg – serious toxicity Greater than 500 mg/kg – potentially lethal.
Asthma research firm Synairgen to float on London’s Alternative Investment Market A spin-out firm from the University of Southampton specialising to find and out-licensing remedies for chronic bronchitis and the severest types of asthma, is going to seek an inventory on London’s Alternative Expenditure Market . World-famous scientist Professor Stephen Holgate and his co-workers Dr Ratko Djukanovic and Dr Donna Davies, who founded Synairgen in the summertime of 2003, possess spent a long time researching the underlying mechanisms of respiratory disease and provide that experience to the business.