One pathological characteristic of Alzheimer’s disease may be the accumulation in the brain of beta-amyloid proteins to create amyloid plaques. However, it is not known how early the plaques forms in the brain, whether they are the primary trigger of the disease or what pathogenic role is played by other changes in the brain. The 1st PET scan in the wonderful world of amyloid plaque in a living individual with the amyloid-binding compound 11C-PIB was performed in 2002 by Professor Agneta Nordberg at Karolinska Institutet on a 56-year old Alzheimer’s patient. The researchers then monitored the individual as the disease progressed with regular PET scans and memory lab tests.Hancox and his co-workers at the University of Otago in Dunedin, say a number of studies have found that sleep-deprived adults and kids are in greater risk of being overweight but theirs may be the first to confirm that short rest during childhood could have long-term implications for adult weight problems. The scholarly study included 1,037 men and women who had been followed since their birth up to age 32 – their parents reported on the usual bedtime and wake-up period when the participants were 5, 7, 9 and 11 years old and the experts say as childhood rest time declined, adulthood body mass index, or BMI, climbed.