CUMC researchers identify gene that seems to play major function in engine neuron degeneration in ALS Explains why some motor neurons are not vulnerable to ALS and factors to potential therapeutic target Columbia University Medical Center experts possess identified a gene, called matrix metalloproteinase-9 , that seems to play a significant role in engine neuron degeneration in amyotrophic lateral sclerosis , also known as Lou Gehrig's disease super-p-force.html . The findings, manufactured in mice, explain why most but not all electric motor neurons are influenced by the disease and recognize a potential therapeutic focus on for this still-incurable neurodegenerative disease.
Start of generic AXERT tabletsMylan announces U.S. Launch of generic Fusilev for InjectionAlnylam presents positive ongoing stage 2 open-label expansion data for Patisiran and RevusiranThe Company’s third party manufacturer intends to respond promptly to the observations, and Cadence programs to request a meeting with the FDA to make sure that the deficiencies have already been adequately addressed to meet the requirements for NDA acceptance. The Company is very pleased with label discussions to date and continues to get authorization of OFIRMEV for the management of discomfort and the reduced amount of fever in adults and children. ‘Cadence is focused on causeing this to be important new medicine available to patients and will continue steadily to work closely with the FDA and our alternative party manufacturer to make sure that the observations are addressed as quickly as possible,’ stated Ted Schroeder, CEO and President of Cadence.