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Data from the dosage expansion phase provided more info on the medical activity and tolerability profile of MEDI4736, showing early proof medical activity in over 300 individuals in multiple tumour types. The Phase I research results, in conjunction with the pre-scientific data and validation of the target, supported the latest acceleration of MEDI4736 into Phase III scientific trials. At the analyst and trader briefing AstraZeneca also verified the enlarged recruitment focus on for the tremelimumab Stage II research in mesothelioma, rendering it a sign up trial. Furthermore to data offered at ASCO, AstraZeneca also supplied an upgrade on the Stage I dose escalation research of MEDI4736 in conjunction with tremelimumab for sufferers with refractory NSCLC.